一、基本情况

姓名：黄政                   出生年月：1989.10            

性别：男                      邮箱：zhenghuang@cqwu.edu.cn

二、个人简述

中共党员，理学博士，副教授，硕士生导师，重庆老员工物医学工程博士后，ylzzcom永利总站线路检测/创新靶向药物国际研究院教学与实验实训中心主任。主要从事药物递送系统等生物医用材料的设计与应用研究，开发了一系列适应于肿瘤微环境的多功能药物共递送载体，实现药物的可控释放，用于肿瘤的靶向化疗/光动力/免疫疗法等。主持重庆市自然科学基金面上项目等省部级科研项目6项，在化学工业出版社出版学术专著1部，获中国发明专利授权3项，近年来在J. Mater. Chem. B、Colloid. Surface. B、ACS Appl. Nano Mater.、Nanomaterials等国际期刊上发表研究论文20多篇。主持省部级教改项目2项，公开发表教改论文2篇。

三、研究领域

药物递送，生物医用材料

四、主持项目情况

1. 重庆市科技局英才项目，构建可操控能量代谢的多功能纳米药物递送系统并应用于逆转多药耐药性，2023/11-2026/10，10万，在研，主持。

2. 重庆市教委重点项目，基于ALPHA和BMS-1的多功能共载纳米系统在PDT和ICB协同治疗三阴性乳腺癌中的应用，2022/07-2025/07，12万，在研，主持。

3．重庆市自然科学基金面上项目，具有聚集诱导发光（AIE）特性的“核-壳”结构仿病毒基因载体研究，2020/07-2023/06，10万元，已结题，主持。

五、发表论文

1. Zheng Huang, Tong Xian, Xiangyi Meng, Huaisong Hu, Lixia Gao, Jiuhong Huang, Donglin Yang, Kepeng Ou, Bochu Wang, Yimei Zhang*, Multifunctional Novel Nanoplatform for Effective Synergistic Chemo-Photodynamic Therapy of Breast Cancer by Enhancing DNA Damage and Disruptions of Its Reparation, Molecules, 2023, 28, 6972.

2. Zheng Huang, Huaisong Hu, Tong Xian, Zhigang Xu, Dianyong Tang, Bochu Wang and Yimei Zhang*, Carrier-free nanomedicines self-assembled from palbociclib dimers and Ce6 for enhanced combined chemo-photodynamic therapy of breast cancer, RSC Adv., 2023, 13, 1617–1626.

3. Zheng Huang, Dan Li, Fang Guo, Tong Xian, Huai-Song Hu, Jia Xu, Ya-Fei Luo, Zhong-Zhu Chen, Bo-Chu Wang and Yi-Mei Zhang*, Mitochondria-targeted photosensitizer based nanoplatform loading glutathione inhibitor for enhanced breast cancer photodynamic therapy, Colloid. Surface. B, 2022, 220, 112956.

4. Zheng Huang, Lixia Gao, Fang Guo, Dan Li, Yan Tang, Huaisong Hu, Yafei Luo, Dianyong Tang, Bochu Wang* and Yimei Zhang*, Novel prodrug supramolecular nanoparticles capable of rapid mitochondrial-targeting and ROS-responsiveness for pancreatic cancer therapy. New J. Chem., 2022, 46, 12632–12640.

5. Yi-Mei Zhang, Meng Xia, Rui Ao, Li-Xia Gao, Yan Tang, Jiu-Hong Huang, Ya-Fei Luo, Zhong-Zhu Chen, Bo-Chu Wang and Zheng Huang*, Smart Design of Mitochondria-Targeted and ROS-Responsive CPI-613 Delivery Nanoplatform for Bioenergetic Pancreatic Cancer Therapy. Nanomaterials, 2021, 11, 2875.

6. Yi-Mei Zhang, Ji Zhang*, Yan-Hong Liu, Yu Guo, Xiao-Qi Yu* and Zheng Huang*, Zinc(II)-cyclen Coordinative Amphiphiles for Enhanced Gene Delivery. RSC Adv., 2020, 10, 39842–39853.

7. Zheng Huang, Dong-Mei Zhao, Xuan Deng, Ji Zhang*, Yi-Mei Zhang and Xiao-Qi Yu*. Functionalized asymmetric bola-type amphiphiles for efficient gene and drug delivery, Nanomaterials, 2018, 8, 115-133.

8. Zheng Huang, Yi-Mei Zhang, Qian Cheng, Ji Zhang*, Yan-Hong Liu, Bing Wang and Xiao-Qi Yu*, Structure–activity relationship studies of symmetrical cationic bolasomes as non-viral gene vectors, J. Mater. Chem. B, 2016, 4, 5575-5584.

9. Zheng Huang, Yan-Hong Liu, Yi-Mei Zhang, Ji Zhang*, Qiang Liu and Xiao-Qi Yu*, Cyclen-based cationic lipids containing a pH-sensitive moiety as gene delivery vectors, Org. Biomol. Chem., 2015, 13, 620-630.

六、获得荣誉和奖励情况

迪康药业奖优秀教师

ylzzcom永利总站线路检测优秀党务工作者

中国发明协会发明创业奖创新奖一等奖